Professor Sunney Ignatius CHAN(陳長謙教授)

Honorary Professor of Chemistrycsi
B.Sc., Ph.D. (Berkeley)
Member of Academia Sinica, Taipei






Honorary Professor of Chemistry, The Chinese University of Hong Kong


Research Interests

Physical biochemistry; structure and function of membrane proteins; bioenergetics; electron and ion transport across biological membranes; bioinorganic chemistry; protein folding; spectroscopic methods for the determination of structure of molecules; magnetic resonance spectroscopy; x-ray spectroscopy and EXAFS.


Representative Publications

1. J. Lin, S.G. Wu and S.I. Chan:
“Electron Transfer from Cytochrome c to 8-azido-ATP-Modified Cytochrome c Oxidase”
Biochemistry, 34, 6335-6343 (1995).
2. S.M. Musser and S.I. Chan:
“Understanding the Cytochrome c Oxidase Proton Pump: Thermodynamics of Redox Linkage”
Biophys. J., 68, 2543-2555 (1995).
3. S. Cavagnero, Z.H. Zhou, M.W.W. Adams and S.I. Chan:
“Response of Rubredoxin from Pyrococcus furiosus to Environmental Changes: Implications for the Origin of Hyperthermostability”
Biochemistry, 34, 9865-9873 (1995).
4. S.M. Musser, M.H.B. Stowell and S.I. Chan:
“Cytochrome c Oxidase: Chemistry of a Molecular Machine”, In: “Advances in Enzymology and Related Areas of Molecular Biology”, Alton Meister, (editor) John Wiley & Sons, Chichester, Publishers (1995) pp. 79-208.
5. B. Wilkinson, M. Zhu, N.D. Priestley, H.-H.T. Nguyen, H. Morimoto, P.G. Williams, S.I. Chan and H.G. Floss:
“A Concerted Mechanism for Ethane Hydroxylation by the Particulate Methane Monooxygenase from Methylococcus capsulatus (Bath)”
J. Am. Chem. Soc., 118, 921-922 (1996).
6. M.H.B. Stowell, R.S. Rock, D.C. Rees and S.I. Chan:
“Efficient Synthesis of Photolabile Alkoxy Benzoin Protecting Groups”
Tetrahedron Letters, 37, 307-310 (1995).
7. H.-H.A.T. Nguyen, M. Zhu, S.J. Elliott, K.H. Nakagawa, B. Hedman, A.M. Costelo, T.L. Peeples, B. Wilkinson, H. Morimoto, P.G. Williams, H.G. Floss, M.E. Lidstrom, K.O. Hodgson and S.I. Chan:
“The Biochemistry of the Particulate Methane Monooxygenase”, In:”Microbial Growth on C1 Compounds”, Mary E. Lidstrom and F. Robert Tabita, editors, Kluwer Academic Publishers, pp. 150-158 (1996).