Professor Gavin Chit TSUI(徐哲教授)

Assistant Professor

location Room 162 Science Centre
Phone No. (852) 3943 6293
Research Group Tsui Research Group Website











2008-2013 Ph.D. University of Toronto, Canada (supervisor: Prof. Mark Lautens)
2004-2006 M.Sc. University of Guelph, Canada (supervisor: Prof. William Tam)
2000-2004 B.Sc. (Hons.) University of Guelph, Canada



2015-present Assistant Professor, The Chinese University of Hong Kong
2013–2015 Postdoctoral Fellow, Max-Planck-Institut für Kohlenforschung, Germany (supervisor: Prof. Benjamin List)
2011 Visiting Scholar, Kyoto University, Japan (supervisor: Prof. Tamio Hayashi)
2007–2008 Research Chemist, Merck & Co., Inc., Canada
2006–2007 Research Associate, NPS Pharmaceuticals, Inc., Canada


Research Interests

Organofluorine chemistry
Metal-mediated reactions
Homogeneous catalysis
Ligand/catalyst design
Medicinal chemistry


Honours and Awards

2018 Asian Core Program Lectureship Award (Japan)
2017 Asian Core Program Lectureship Award (Korea, Singapore)
2016 Thieme Chemistry Journals Award
2013 Humboldt-Bayer Research Fellowship for Postdoctoral Researchers
2013 Boehringer Ingelheim Award of Excellence in Organic or Bio-Organic Chemistry
2011 JSPS Summer Program Fellowship
2009 Alexander Graham Bell Canada Graduate Scholarship (CGS)
2009 Ontario Graduate Scholarship (OGS)


Publications (since independent career)


1. Perfluoroalkylation of Thiosulfonates: Synthesis of Perfluoroalkyl Sulfides. Luo, Z.; Yang, X.; Tsui, G. C. Org. Lett. 2020, asap. ChemistryViews news.
2. Palladium-Catalyzed Stereoselective Hydrodefluorination of Tetrasubstituted gem-Difluoroalkenes. Ma, Q.; Liu, C.; Tsui, G. C. Org. Lett. 2020, 22, 5193-5197.
3. Radical Pentafluoroethylation of Unactivated Alkenes Using CuCF2CF3. Yang, X.; Tsui, G. C. Org. Lett. 2020, 22, 4562-4567.
4. Stereoselective Palladium‐Catalyzed C−F Bond Alkynylation of Tetrasubstituted gem‐Difluoroalkenes. Ma, Q.; Wang, Y.; Tsui, G. C. Angew. Chem. Int. Ed. 2020, 59, 11293-11297.
5. Silver-Catalyzed Trifluoromethylalkynylation of Unactivated Alkenes with Hypervalent Iodine Reagents. Yang, X.; Tsui, G. C. Org. Lett. 2019, 21, ​8625-8629.
6. Trifluoromethylation of Anthraquinones for n-Type Organic Semiconductors in Field Effect Transistors. Zhao, M.; Yang, X.; Tsui, G. C.; Miao, Q. J. Org. Chem. 2020, 85, ​44-51. (collaboration)
7. Trifluoromethylation of Unactivated Alkenes with Me3SiCF3 and N-Iodosuccinimide. Yang, X.; Tsui, G. COrg. Lett2019, 21, 1521-1525. (one of the most downloaded papers in Feb 2019)
8. Domino Cyclization/Trifluoromethylation of 2-Alknylphenols for the Synthesis of 3-(Trifluoromethyl)benzofurans and Evaluation of Their Antibacterial and Antifungal Activities. Li, M.; Ye, Y.; He, L.; Hui, M.; Ng, T. B.; Wong, J. H.; Tsui, G. C. Asian J. Org. Chem. 2019.
9. Trifluoromethylation of α-Diazoesters and α-Diazoketones with Fluoroform-Derived CuCF3: Synergistic Effects of Co-Solvent and Pyridine as a Promoter. Ma, Q.; Tsui, G. C. Org. Chem. Front2019, 6, 27-31.
10. Copper-Mediated 1,2-Bis(trifluoromethylation) of Arynes. Yang, X.; Tsui, G. C. Chem. Sci2018, 9, 8871-8875.
11. Domino Cyclization/Trifluoromethylation of 2-Alkynylanilines Using Fluoroform-Derived CuCF3: Synthesis of 3-(Trifluoromethyl)indoles. Ye, Y.; Cheung, K. P. S.; He, L.; Tsui, G. C. Org. Chem. Front2018, 5, 1511-1515.
12. Synthesis of 2-(Trifluoromethyl)indoles via Domino Trifluoromethylation/Cyclization of 2-Alkynylanilines. Ye, Y.; Cheung, K. P. S.; He, L.; Tsui, G. C. Org. Lett2018, 20, 1676-1679.
13. Copper-Mediated Domino Cyclization/Trifluoromethylation of Propargylic N‐Hydroxylamines: Synthesis of 4‐Trifluoromethyl-4- isoxazolines. Wang, Q.; Tsui, G. C. J. Org. Chem2018, 83, 2971-2979.
14. Copper-Mediated Trifluoromethylation-Allylation of Arynes. Yang, X.; Tsui, G. C. Org. Lett2018, 20, 1179-1182.
15. Domino Hydroboration/Trifluoromethylation of Alkynes Using Fluoroform-Derived CuCF3. He, L.; Yang, X.; Tsui, G. C. J. Org. Chem2017, 82, 6192-6201.
16. Copper(I)-Catalyzed Interrupted Click Reaction with TMSCF3: Synthesis of 5-Trifluoromethyl 1,2,3-Triazoles. Cheung, K. P. S.; Tsui, G. C. Org. Lett2017, 19, 2881-2884.
17. Hydroxytrifluoromethylation of Alkenes Using Fluoroform-Derived CuCF3. Yang, X.; He, L.; Tsui, G. C. Org. Lett2017, 19, 2446-2449.
18. Synthesis of Fluorescent Indazoles by Palladium-Catalyzed Benzannulation of Pyrazoles with Alkynes. Kim, O. S.; Jang, J. H.; Kim, H. T.; Han, S. J.; Tsui, G. C.Joo, J. M. Org. Lett2017, 19, 1450-1453.
19. Copper-Mediated Domino Cyclization/Trifluoromethylation/Deprotection with TMSCF3: Synthesis of 4-Trifluoromethylpyrazoles. Wang, Q.; He, L.; Li, K. K.; Tsui, G. C. Org. Lett2017, 19, 658-661.
20. Fluoroform-Derived CuCF3 for Trifluoromethylation of Terminal and TMS-Protected Alkynes. He, L.; Tsui, G. C. Org. Lett2016, 18, 2800-2803.
21. Review: Fluoroform, First Update. He, L.; Tsui, G. C., In Encyclopedia of Reagents for Organic Synthesis, Rovis, T. Ed.; Wiley-VCH: Weinheim, 2017.
22. Book chapter: Five-Membered Ring Systems: Furans and Benzofurans. Ke, Z.; Tsui, G. C., Peng, X.-S.; Yeung, Y.-Y., In Progress in Heterocyclic Chemistry, Gribble, G. W.; Joule, J. A. Eds.; Elsevier: Oxford, 2016 to present.