Professor Dennis Kee Pui NG(吳基培教授)

CChem FRSC CSci
Professor

location    Room 358 Science Centre

Phone No.    (852) 3943 6375

Fax No.    (852) 2603 5057

Email    dkpn@cuhk.edu.hk

0000-0001-9087-960X

 

 

 

 

Education

1990-1993 D.Phil. in Chemistry
Balliol College, University of Oxford
1988-1990 M.Phil. in Chemistry
The Chinese University of Hong Kong
1984-1988 B.Sc. (Hons.) in Chemistry, First Class
Chung Chi College, The Chinese University of Hong Kong

 

Honours and Awards

2000, 2009, 2013,2020 Faculty Exemplary Teaching Award, The Chinese University of Hong Kong
2009 The Vice-Chancellor’s Exemplary Teaching Award, The Chinese University of Hong Kong
2005 Young Researcher Award, The Chinese University of Hong Kong
1990-1993 Croucher Foundation Scholarship
1988-1990 Croucher Foundation Studentship

 

Positions

Since 2002 Professor, Department of Chemistry, The Chinese University of Hong Kong
Since 2002 Warden, Pentecostal Mission Hall Complex (High Block)  Chung Chi College, The Chinese University of Hong Kong
2017-2021 Pro-Vice-Chancellor/Vice-President, The Chinese University of Hong Kong
2019-2020 Acting University Dean of Students, The Chinese University of Hong Kong
2011-2017 Associate Vice-President, The Chinese University of Hong Kong
2009-2017 University Dean of Students, The Chinese University of Hong Kong
2004-2008 Associate Dean (Student Affairs), Faculty of Science, The Chinese University of Hong Kong
2002-2005 Part-Time Professor, Fuzhou University, China
2001-2004 Associate Director, Applied Chemistry with Management Studies Programme, The Chinese University of Hong Kong
1997-2000 Part-Time Lecturer, School of Pharmacy, The Chinese University of Hong Kong
1994-2002 Lecturer in Chemistry, The Chinese University of Hong Kong
1993-1994 Research Fellow in Chemistry, California Institute of Technology, USA

 

Professional Qualifications

Nov. 2004 Chartered Scientist (CSci), Science Council, UK
Jul. 2000 Fellow of the Royal Society of Chemistry (FRSC)
Mar. 1993 Chartered Chemist, Member of the Royal Society of Chemistry (CChem MRSC)

 

Teaching Experience

A. Undergraduate
Teaching Subjects:
Transition Metal Chemistry, Fundamental of Spectroscopic Analysis
B. Postgraduate
Being the supervisor of 37 Ph.D. students (30 of them have completed their study) and 14 M.Phil. students (all of them have graduated)
Group Members (Past & Present)

 

Research Interests

Our current research interests lie in the chemistry of various functional dyes, particularly phthalocyanines and boron dipyrromethene derivatives, focusing on their synthesis, supramolecular chemistry, bioconjugation, bioorthogonal chemistry and applications in photodynamic therapy, photothermal therapy, bioimaging, fluorescence sensing, logic devices and renewable energy production.
The ongoing projects include:
A. Design and preparation of multifunctional molecular and nano-photoresponsive agents for targeted phototherapies
B. Use of supramolecular and bioorthogonal chemistry for advanced theranostic applications
C. Development of efficient peptide and protein conjugation methods
D. Development of molecular-based fluorescent sensors and logic devices
E. Synthetic studies and applications of low-symmetry phthalocyanines
F. Exploration of phthalocyanine-based materials for CO2 fixation, water splitting and batteries

Publications

Full List of Publications
Total Number of Publications = 245
Number of Citations = 9,514
H-index = 59
(taken from Scopus as of June 20, 2022)

 

External Research Grants (As Principal Investigator for the last 5 years)

(1)  Project:    Selective Photodynamic Eradication of Senescent Cells with b-Galactosidase-Activated Photosensitizers (Ref. No. CUHK14307518)

Grant:      RGC General Research Fund 2018-19 – HK$ 505,298

Period:     Jan. 1, 2019 – Dec. 31, 2021

 

(2)  Project:    Targeted Delivery and Activation of Photosensitizers for Photodynamic Therapy using Supramolecular Bioorthogonal Chemistry (Ref. No. CUHK14307719)

Grant:      RGC General Research Fund 2019-20 – HK$ 558,272

Period:     Sep. 1, 2019 – Aug. 31, 2022

 

(3)  Project:    Tumor-Selective Activatable Polydopamine-Based Nanophotosensitizers for Targeted Photodynamic Therapy (Ref. No. CUHK14306320)

Grant:      RGC General Research Fund 2020-21 – HK$ 441,074

Period:     Sep. 1, 2020 – Aug. 31, 2023

 

(4)  Project:    Dual Receptor-Mediated Endocytosis of Bioorthogonal Components for Site-Specific Activation of Photodynamic Therapy (Ref. No. CUHK14307321)

Grant:      RGC General Research Fund 2021-22 – HK$ 806,375

Period:     Sep. 1, 2021 – Aug. 31, 2024

 

(5)  Project:    Development of Novel Cell Penetrating Peptide-Conjugated Drugs for Treatment of Ocular Uveitis (Ref. No. PRP/015/21FX)

Grant:      Innovation and Technology Commission (ITC) Partnership Research Programme – HK$ 1,715,800

ITC Research Talent Hub – HK$ 3,291,635

Period:     Feb. 4, 2022 – Jul. 31, 2024

Editorial Work

  • Editorial Board Member, Colorants
  • Editorial Board Member, Nanomaterials
  • Guest Editor for the “Special Collection on Photodynamic Therapy” in ChemPlusChem