Professor LAU, Shing Hing Michael(劉承鑫教授)

Assistant Professor

location Room G58 Science Centre
location (852) 3943 8126











2013-2017 Ph.D. University of Cambridge (Supervisor: Prof. Steven V. Ley CBE FRS FRSC)
2008-2013 MSci Imperial College London (Supervisor: Prof. Donald Craig)


Research Interests

My research interests focus on developing new chemical methodologies and processes with the use of enabling technologies for potential industrial applications, for instance, robust and scalable syntheses of active pharmaceutical ingredients, agrochemical compounds and biofunctional polymer materials.


Honours and Awards

2013-2017 The Croucher Cambridge International Scholarship, The Croucher Foundation
2016 Lundgren Research Award, University of Cambridge
2012 IC/UCL Research Studentship in Catalysis, IC and UCL


Representative Publications

1. Forni, J. A.; Lau, S. -H.; Poh, J. -S.; Battilocchio, C.; Ley, S. V.; Pastre, J. C. “Diastereoselective Synthesis of Functionalized Indolines Using in situ Generated Allyl Boronic Species” Synlett20186, 825-829.
2. Bomio, C.; Kabeshov, M. A.; Lit, A. R.; Lau, S. -H.; Ehlert, J.; Battilocchio, C.; Ley, S. V. “Unveiling the role of boroxines in metal-free carbon–carbon homologations using diazo compounds and boronic acids” Chem. Sci. 20178, 6071-6075.
3. Battilocchio, C.; Lau, S. -H.; Hawkins, J. M.; Ley, S. V. “Continuous Flow Hydration of Pyrazine-2-carbonitrile in a Manganese Dioxide Column Reactor” Org. Synth. 201794, 34-45.
4. Poh, J. -S.; Lau, S. -H.; Dykes, I. G.; Tran, D. N.; Battilocchio, C.; Ley, S. V. “A multicomponent approach for the preparation of homoallylic alcohols” Chem. Sci. 20167, 6803-6807.
5. Lau, S. -H.; Galván, A.; Merchant, R. R.; Battilocchio, C.; Souto, J. A.; Berry, M. B.; Ley, S. V. “Machines vs malaria: a flow-based preparation of the drug candidate OZ439” Org. Lett. 201517, 3218- 3221.
6. Lau, S. -H.; Bourne, S. L.; Martin, B.; Schenkel, B.; Penn, G.; Ley, S. V. “Synthesis of a precursor to sacubitril using enabling technologies” Org. Lett. 201517, 5436-5439.
7. Martin, B.; Penn, G.; Schenkel B.; Bourne, S.; Lau, S. -H.; Ley, S. V. “New Processes and Intermediates Useful in Synthesis of NEP Inhibitors” – USP 62/222,249, 2015, Filed.
8. Barreiro, E.; Sanz-Vidal, A.; Tan, E.; Lau, S. -H.; Sheppard, T. D.; Díez-González, S. “HBF4-Catalysed Nucleophilic Substitutions of Propargylic Alcohols” Eur. J. Org. Chem. 2015, 7544-7549.