Professor Fuk Yee KWONG(鄺福兒教授)

Professor and Department Chairman

location Room G56 Science Centre

Phone No. (852) 3943 6257

Email fykwong@cuhk.edu.hk

Research Group Kwong Research Group

0000-0001-9105-1740

 

 

 

 

Education

2003 Postdoc, Department of Chemistry,
Massachusetts Institute of Technology (MIT), USA
2000 Ph.D., Department of Chemistry,
The Chinese University of Hong Kong
1996 B.Sc., Department of Applied Biology and Chemical Technology
The Hong Kong Polytechnic University

 

 

Honours and Awards

2019 Asian Core Program Lectureship Award
The Asian Core Program (China)
2019 The Distinguished Lectureship Award, The CSJ Asian International Symposium
The Chemical Society of Japan
2016 Asian Core Program/ Advanced Research Network Lectureship Award
The Asian Core Program (Japan)
2014 Higher Education Outstanding Scientific Research Output Awards (Science and Technology) Second-class Award in Natural Science
Ministry of Education, PR China (教育部高等學校科學研究優秀成果獎自然科學二等獎)
2014 Rising Star Award
41st International Conference on Coordination Chemistry
2013 Asian Core Program Lectureship Award
The Asian Core Program (Korea)
2013 The Croucher Senior Fellowship
The Croucher Foundation, Hong Kong
2012 The President’s Awards on Excellent Achievement in Research & Scholarly Activities
The Hong Kong Polytechnic University
2012 Asian Core Program Lectureship Award
The Asian Core Program (Thailand)
2011 Asian Core Program Lectureship Award
The Asian Core Program (China)
2010 Asian Core Program Lectureship Award
The Asian Core Program (Japan)
2010 Asian Core Program Lectureship Award
The Asian Core Program (Singapore)
2001 Croucher Postdoctoral Fellowship
The Croucher Foundation, Hong Kong

 

 

Position

Since 2021 Chairman, Department of Chemistry, The Chinese University of Hong Kong
Since 2018 Director,
Shenzhen Municipal Key Laboratory of Chemical Synthesis of Medicinal Organic Molecules
Shenzhen Centre of Novel Functional Molecules, The Chinese University of Hong Kong Shenzhen Research Institute
(新颖功能分子研究中心, 深圳市药用有机小分子化学合成重点实验室, 香港中文大学深圳研究院)
Since 2017 Professor,
Department of Chemistry, The Chinese University of Hong Kong
2016-2017 Associate Head,
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University
2014-2017 Professor,
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University
2010-2014 Associate Professor,
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University
2004-2010 Lecturer/ Assistant Professor
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University

 

 

Professional Activities

Since 2020 Elected Member,
The Hong Kong Young Academy of Sciences
(香港青年科學院青年院士)
Since 2019 Committee Member on Science Education,
Curriculum Development Council
(課程發展議會科學教育委員會委員)

 

 

Research Interests

Our research group has broad interests in synthetic organic chemistry and organometallics chemistry. Current areas of focus include:

1. Design, preparation, and application of new phosphine ligands
2. Development of new transition metal-catalyzed C-H bond functionalization for carbon-carbon and carbon-heteroatom bond formation
3. Organocatalysis / Cross-Dehydrogenative-Coupling Methodologies
4. Enantioselective reactions

 

 

Representative Publications

Book Chapters

1. Pui Ying Choy, Xinwei He and Fuk Yee Kwong*
“Palladacycles as Precatalysts for Heck and Sonogashira Cross-Coupling Reactions” in Palladacycles: Catalysis and Beyond,
Kapdi, A.; Maiti, D. Eds., Elsevier (2019), pp. 21-173
2. Shun Man Wong, and Fuk Yee Kwong*
“Nondirected C-H Bond Functionalizations of (Hetero)arenes” in Strategies for Palladium-Catalyzed Non-Directed and Directed C-H Bond Functionalization,
Anant R. Kapdi and Debabrata Maiti (Eds) Elsevier Inc. (2017), 49-116.
3. Shun Man Wong, Chau Ming So and Fuk Yee Kwong*
“Ligand-Enabled Palladium-Catalyzed C-N and C-O Bond Formations from Aryl Halides, Tosylates and Mesylates” in Applied Homogeneous Catalysis with Organometallic Compounds,
Boy Cornils, Wolfgang A. Hermann, Matthias Beller and Rocco Paciello (Eds) Wiley-VCH: Weinheim (2017), 411-464.
4. Pengfei Li, Jun Wang and Fuk Yee Kwong*
“Asymmetric Michael addition and related reactions” in Stereoselective Synthesis of Drugs and Natural Products,
Vasyl Andrushko and Natalia Andrushko (Eds) John Wiley & Sons (2013), 249-270.
5. Yinuo Wu, Jun Wang and Fuk Yee Kwong*
“C-C Cross-Couplings of Acidic C-H Nucleophiles” in Cross-Coupling and Heck-Type Reactions Vol. 1-3,
Gary A. Molander and John P. Wolfe (Eds) Georg Thieme (2012), Ch. 2.7.2.
6. Fuk Loi Lam, Hang Wai Lee, Jun Wang and Fuk Yee Kwong*
“Recent Advancement of Catalytic Pauson-Khand-type Reactions” in The Pauson-Khand Reaction: Scope, Variations and Applications,
Ramon Rios Torres (Eds) John Wiley & Sons, (2012), 181-210.

 

Representative Publications

1. Wai Chung Fu, Fuk Yee Kwong*
“A denitrogenative palladium-catalyzed cascade for regioselective synthesis of fluorenes”
Chem. Sci. 202011, 1411-1417.
2. Mingliang Li, Fuk Yee Kwong*
“Cobalt-Catalyzed Tandem C–H Activation/C–C Cleavage/C–H Cyclization of Aromatic Amides with Alkylidenecyclopropanes”
Angew. Chem., Int. Ed. 2018, 57, 6512-6516. (chosen as Front-Cover Picture)
3. Qingyang Zhao, Wai Chung Fu, Fuk Yee Kwong*
“Palladium-Catalyzed Regioselective Aromatic Extension of Internal Alkynes through a Norbornene-Controlled Reaction Sequence”
Angew. Chem., Int. Ed. 2018, 57, 3381-3385.
4. Wai Chung Fu, Zheng Wang, Wesley Ting Kwok Chan, Zhenyang Lin, Fuk Yee Kwong*
“Regioselective Synthesis of Polycyclic and Heptagon-embedded Aromatic Compounds through a Versatile π-Extension of Aryl Halide.”
Angew. Chem., Int. Ed. 2017, 56, 7166-7170.
5. On Ying Yuen, Chau Ming So, Ho Wing Man, Fuk Yee Kwong*
“A General Palladium-Catalyzed Hiyama Cross-Coupling Reaction of Aryl and Heteroaryl Chlorides”
Chem. –Eur. J. 2016, 22, 6471-6476. (chosen as HOT paper and Inside Back Cover)
6. Bao-Min Fan*, Qing-jing Yang, Jun Hu, Cai-ling Fan, Si-feng, Li, Lu Yu, Chao Huang, Wing Wai Tsang, Fuk Yee Kwong*
“Asymmetric Hydroalkynylation of Norbornadienes Promoted by Chiral Iridium Catalysts”
Angew. Chem. Int. Ed. 201251, 7821-7824.
7. Chau Ming So, Fuk Yee Kwong*
“Palladium-catalyzed cross-coupling reactions of aryl mesylates”
Chem. Soc. Rev. 201140, 4963-4872.
8. Wei Liu, Hao Cao, Hua Zhang, Heng Zhang, Kin Ho Chung, Chuan He, Haibo Wang, Fuk Yee Kwong*, Aiwen Lei*
“Organocatalysis in Cross-Coupling: DMEDA-Catalyzed Direct C-H Arylation of Unactivated Benzene”
J. Am. Chem. Soc. 2010132, 16737-16740. (Top 1% highly cited paper in 2015-2019)
9. Pui Yee Yeung, Chau Ming So, Chak Po Lau, Fuk Yee Kwong*
“A General and Efficient Palladium-Catalyzed Cyanation of Aryl Mesylates in Water or Water/t-BuOH Medium”
Angew. Chem., Int. Ed. 201049, 8918-8922. (chosen as HOT paper)
10. Hang Wai Lee, Fuk Loi Lam, Chau Ming So, Chak Po Lau, Albert S. C. Chan, Fuk Yee Kwong*
“Palladium-Catalyzed Cross-Coupling of Aryl Halides Using Organotitanium Nucleophiles”
Angew. Chem., Int. Ed. 200948, 7436-7439. (chosen as HOT paper)
11. Chau Ming So, Chak Po Lau, Fuk Yee Kwong*
“A general palladium-catalyzed Suzuki-Miyaura coupling of aryl mesylates”
Angew. Chem., Int. Ed. 200847, 8059-8063.
12. Chau Ming So, Chak Po Lau, Fuk Yee Kwong*
“Palladium-Catalyzed Amination of Aryl Mesylates”
Angew. Chem., Int. Ed. 200847, 6402-6406.

 

Representative Patents

1. 邝福儿*, 李东昇; 蔡珮盈
“苯并咪唑-吲哚骨架的膦配体及其制备方法和应用”
中国专利, 2018, CN107459533B.
2. 邝福儿*, 苏秋铭; 周永健; 原安莹
“一种吲哚骨架的膦配体及其制备方法和应用”
中国专利, 2018, CN107445989B.
3. Fuk Yee Kwong*, Shun Man Wong, Chung Chiu Yeung
“Novel phosphines, synthesis thereof and their use in catalysis”
US Patent, 2018, US10093692B2.
4. 邝福儿*, 蔡珮盈; 苏秋铭; 原安莹
“(2-二取代膦苯基)-1-烷基-吲哚膦配体及其合成方法和应用”
中国专利, 2018, CN104945434B.
5. Fuk Yee Kwong*, Pui Ying Choy, Yinuo Wu, Qingjing Yang
“Synthesis of Phosphine Ligands Bearing Tunable Linkage: Methods of Their Use in Catalysis”
World Patent, 2017, WO 2017/193288.
6. Fuk Yee Kwong*, Shun Man Wong
“Novel benzimidazolyl phosphines as ligands for transition metal-catalyzed coupling and amination reactions”
World Patent, 2015, WO 2015/039606.
7. Fuk Yee Kwong*, Chau Ming So
“Ligand for transition metals and methods of use”
US Patent, 2012, US 8212056.
8. Fuk Yee Kwong*, Chau Ming So
“Ligand for transition metals and methods of use”
US Patent, 2009, US 12216080.